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Title : Obesity-cancer-Enhancing Risk Factor
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Obesity-cancer-Enhancing Risk Factor

Obesity makes a path to various diseases and ailments. One of the fatal disease is cancer . Obesity promotes many health risks, including cancer. Being fat increases the odds of death by cancer in the future.

A study published in The New England Journal of Medicine revealed that weight loss can prevent more 90,000 deaths cancer.

What is obesity :?

Abnormal presentation of the body in which a person high proportion unhealthy and faces body / fat mass .

To measure obesity, a scale is commonly used by researchers called Body Mass Index (BMI) . It is calculated by dividing a person's weight by their height. It is the most accurate form measure obesity. The normal BMI score is between 21 and 23 kg / m2 ( According to the current recommendations of the public health objectives of the Global Research cancer (WCRF)

Insight ratio obesity cancer

studies have explored why obesity has led to an increased risk of cancer and the growth of cancer cells. obese people have more fatty tissue people than normal, and that is why they produce more hormones which may result in the growth of cancer cells excess body fat promotes.

factor-1 , a hormone improvement of cancer

1. insulin-like growth. High levels of factor-1 cells cause-like-insulin growth to grow faster, leading to a cancerous condition.
2. also affects immune system function and level or subacute chronic inflammation of low
3. levels peculiar hormones like insulin and estrogen
4. also affects proteins influence the way our body uses some hormones like binding globulin sex hormone

the sync may also affect cancer risk. Studies suggest the following responsible for affecting cancer risk factors

• More weight gain childhood or adulthood it is also one of the reasons of an increased risk of cancer. For example, most women who are obese in their teens are more likely to develop ovarian cancer before menopause.
• losing and gaining weight again ( cycling weight ) may also be a risk factor for cancer

therefore, the importance of maintain a healthy weight is associated with a decrease in most diseases and illnesses including cancer .

biological mechanism related to abdominal obesity with cancer susceptibility

The mechanisms that can promote cancer development or progression in obese or overweight people generally fall into two types . They can be:

• universal in nature
• direct in nature

specific site apply to most tumors and may have . Several synthesis mechanism can be carried out differently in different people:

Diet:

Studies and experiments suggest that changes in diet quality and caloric intake may significantly affect the risk of progression cancer and development. But limited intake calorie long term decreases the incidence of cancer. Low High fiber diet of cereals, high consumption of fruits and vegetables and in insulin carbohydrate inhibiting the diet also says it is good to limit the risk of cancer. A study also confirmed that low vitamin D handles 20% increase in cancer risk after the increase (Mass Index Bone) BMI

physical Activity

brisk walking, exercise and others physical activities a at home can prevent the incidence of diseases including breast, colon and endometrial cancer in particular.

Insulin Resistance:

Obesity and adiposity (high fat) are directly associated with insulin resistance that compensates pancreatic insulin secretion , and the result is hyperinsulinemia . These elevated insulin levels served as faster growth and greater aggressiveness of the following cancers:

• colorectal
• pancreas
• Liver
• postmenopausal breast cancer
• endometrial cancer

Sex Hormones:

in women, BMI (Body Mass Index Bone) correlates with:

Since in the development of cancer, an increase in circulating sex steroids obesity is a well known mechanism.

Chronic inflammation

A chronic inflammatory response is an inclination towards obesity than other initiates and promotes cancer . In chronic inflammation low, energy expenditure is reduced , and energy is conserved leads to obesity.

Obesity-induced hypoxia

A transcription factor (HIF-1α) which is associated with increased metastatic spread and can lead to melanoma (skin cancer)

Oxidative stress:

oxidative increase DNA damage may increase the risk of cancer. systemic oxidative stress increases.

Relationship of certain cancers with obesity

There are some cancers that are closely related to weight. Excess fat is associated with improvements of risk of cancer:

• The breast
• womb
• colon and rectum
• Kidney
• Esophagus
• gallbladder
• endometrium
• pancreatic

Tips for maintaining a healthy body weight and how Lowers cancer risk

maintaining a healthy body weight is important for overall health. Obese people face many health challenges. Exercise good nutrition and lifestyle changes are forms to lose weight and improve health.

Start with the aim of lose 5 to 10% of body weight. adequate physiotherapy exercises can help you lose weight along with a good nutritional plan. Otherwise, medication or surgery is the next option.

Certain hormones like insulin, androgens and estrogens , decreased after losing weight help in reducing cancer risk.

Conclusion:

Overweight or obesity is responsible for approximately 20% of malignant tumors. While changes in lifestyle and exercise can greatly reduce susceptibility to cancer. Therefore, there is a strong relationship cancer obesity .

References

1. Obesity: A risk factor for certain cancers
2. obesity a risk factor for cancer
3. obesity, weight and cancer
4. Does it affect the body weight of cancer
5. facts and evidence body weight
6. obesity and cancer risk
7. Does factor overweight risk cause cancer

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