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Title : New HIV vaccine that was tested in South Africa
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New HIV vaccine that was tested in South Africa

The vaccine has been enhanced for use in higher risk populations in sub-Saharan Africa, where there is also a different virus subtype.

"We have inserted specific inserts viruses that have broken off from the subcontinent," said Gail Bekker. A new component was also introduced to stimulate stronger immunity, known as an adjuvant.

four criteria are established as possible efficacy measures, including the level of T cells and antibody response to fight the virus if it were to infect.

"Give the signal at the four, which has a promising aspect and should start," said Gail Bekker. "We wanted to see a particular image of immunity suggests that a large trial would be likely to produce effective results," he said.

"[This] was the guardian of will or we will not move forward," Fauci said, "and the answer is 'yes'."

In a larger trial of the vaccine now start at 5,400 people at four sites in South Africa in November 2016 and last for three years. A fifth dose of the vaccine will also be given in the hope of longer lasting protection.

The Thai study showed 60% protection against HIV after one year, but the figure dropped to 31% at the end of the trial. The team hopes that the new regime will bring levels of backup protection.

"Give the signal at the four, which has a promising aspect and should start," said Gail Bekker. "We wanted to see a particular image of immunity suggests that a large trial would be likely to produce effective results," he said.

"[This] was the guardian of will or we will not move forward," Fauci said, "and the answer is 'yes'."

In a larger trial of the vaccine now start at 5,400 people at four sites in South Africa in November 2016 and last for three years. A fifth dose of the vaccine will also be given in the hope of longer lasting protection.

The Thai study showed 60% protection against HIV after one year, but the figure dropped to 31% at the end of the trial. The team hopes that the new regime will bring levels of backup protection.

"I do not think we will try to [our] way out of this epidemic," said Gail Bekker. "We are ultimately we will need a vaccine to turn it off."

The first vaccines available are unlikely to provide sufficient protection for use on their own, but instead are needed in combination with the plethora of prevention, treatment and social interventions that are already In use.

"A vaccine is still of great importance to the epidemic," said Sharon Lewin, director of Peter Doherty Institute for Infection and Immunity. "Even though we have all these prevention options, nothing will be as good as a vaccine."


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