Title : Show me Corps - Performance Enhancing Drugs and cardiovascular risk
link : Show me Corps - Performance Enhancing Drugs and cardiovascular risk
Show me Corps - Performance Enhancing Drugs and cardiovascular risk
Iron Mike Arnold Mag
seems like yesterday, in the premiere, stronger, faster, bodybuilders steroid use were treated with number of reassuring comments from industry experts, large movie stating anabolic steroids were grossly misrepresented in terms of health risk. Presented as innocent victims of a witch hunt by the government-media, promoted the message was clear-steroids were a relatively safe category, if not benign performance enhancers. While higher organisms, undoubtedly helped in spreading false information, causing the social perception of these drugs deteriorate further, the response-characterized by an almost total rejection of the bodybuilding community risk was equally damaging, that only serves to damage the health and long-term credibility of its participants.
Over time, a particular quote the film took on a life of its own, becoming a sort of slogan among those trying to minimize health risks perceived their chosen lifestyle. originally stated by John Romano, "Show me the bodies" was an interesting choice of words. A purely defensive comment is to draw attention to the fact that steroids are almost never appear as an official cause of death, while indirectly refute the assertion that increase mortality. As a result, many bodybuilders are lulled into a false sense of security and more emboldened in its drug abuse.
This is faulty logic, however, as the sole purpose of the "cause of death" on a death certificate is to indicate the immediate and the underlying cause (s) of death. For example, if someone dies of cardiac arrest, the immediate cause of death could be classified as acute myocardial infarction (ie heart attack), while the underlying cause of death could be listed as the disease coronary arteries (i.e., atherosclerosis). As we all know, there are many potential risk factors in the development of cardiovascular diseases such genetics, obesity, smoking, poor diet, etc. However, you will not find "McDonald and Krispy Kreme He ate every day for the last 20 years," it appears as an official cause of death because the coroner should be able to show proof of his claims, pointing to a demonstrable pathology (diagnosable conditions directly related to the immediate cause of death), rather than relying on speculation, no matter how likely it could be.
Although much of the information presented below has been known for certain factions of the medical community for decades, science continues to reveal new and disturbing information regarding the harmful effects of aspirin on cardiovascular health. At this point, the evidence is clear steroid use is a major risk factor in the development of several cardiovascular conditions, many of which can lead to serious or life-threatening complications (ie, heart failure, heart attack, stroke, etc). Given the great importance of this body system in good working order, all bodybuilders should be educated on the basic risks involved, since it is the first critical step in the prevention process.
Some of the most concerning side effects of aspirin on the cardiovascular system are: increased blood pressure, dyslipidemia (abnormal lipid profile), cardiomyopathy (heart muscle disease / abnormality) left ventricular hypertrophy (a specific cardiomyopathy associated with increased mortality), high hematocrit / hemoglobin, improved and several issues of the heart valves platelet aggregation. Of these, high blood pressure is probably the most insidious of the group, since it is easy to diagnose, but often asymptomatic. In addition to cardiovascular dysfunction, high blood pressure is also the # 1 cause of kidney damage in the bodybuilders around the world.
When blood pressure, the heart has to work harder to supply enough blood to the body rises. This causes the heart muscle to thicken (hypertrophic cardiomyopathy), in its effort to compensate for the increased workload being imposed. Over time, the heart muscle weakens, contractile force is decreased, and may have difficulty relaxing. This prevents the heart to fill with blood properly, finally culminating in heart failure. Heart failure is a serious condition characterized by the heart's inability to pump an adequate amount of blood in the body, including the heart itself. If left unresolved, the end result is a heart attack.
In addition to increased blood pressure, AAS are also capable of causing cardiomyopathy through overstimulation of the androgen receptor (AR) in cardiac muscle. Unfortunately, AAS are not selective when it comes to AR stimulation. Instead of attaching exclusively to Ars in skeletal muscle (which is the goal of S.A.R.Ms) that circulate throughout the body, engaging and activating any contact AR. As a muscle, the heart is receptive to stimulation of AR in the same way that skeletal muscle is induced growth, although some have proposed that may have a comparatively low degree of susceptibility. In any case, steroids have been shown to induce significant cardiac hypertrophy, especially when combined with weight training.
There are three main types of dilated cardiomyopathy: restrictive, and hypertrophic. Of these, hypertrophic and dilated are the most common types experienced by consumers of EAA. often caused by high blood pressure and disease of the coronary arteries (common side effects of use AAS), dilated cardiomyopathy usually begins in the left ventricle (main pumping chamber of the heart) and then spreads to other areas of heart. It is characterized by one (ie, expansion) of stretching and thinning of the heart muscle. This makes the inside of the chamber to enlarge, preventing contract normally. This directly reduces cardiac output and total blood flow to the body. If allowed to fester unchecked, the heart will continue to weaken, leading to other diseases such as heart failure, blood clots, valve problems, and heart attack / stroke.
Hypertrophic cardiomyopathy is defined as an abnormal thickening of the heart muscle (especially the left ventricle) and can be caused by high blood pressure, receptor activation of AR, and sports training (especially intensive training with weights). Many of the problems associated with this type of cardiomyopathy are precipitated by muscle dysfunction. This is because the heart muscle tends to harden as it grows, resulting in mechanical-electrical disturbances similar to those found with restrictive cardiomyopathy potentially serious. This includes heart failure, valve problems, blood clots, and even dilated cardiomyopathy. The endpoints are heart attack, stroke, etc.
Most doctors agree that the most dangerous form of hypertrophic cardiomyopathy and users in AAS are more susceptible to ventricular hypertrophy, which is also known as LVH. To understand why it is so important to keep this chamber of the heart working properly, let's take a brief look at their role in the cardiovascular system.
When the heart receives oxygen-rich blood from the lungs, the first place you go is the left atrium, after which moves the most powerful ventricle-left of all chambers of the heart and responsible for maintaining circulation. This thick muscle has to be able to perform intense contractions so you can force blood to all parts of the body. As prime mover heart, even moderate dysfunction can cause death, so it is not surprising that LVH has received so much emphasis on steroid users. Unfortunately, the failure of the left ventricle is a much more common cause of heart failure / heart attack than the failure of the right ventricle. Moreover, even when failure is experienced right, usually it is caused by problems arising from the left. Because of this, LVH is strongly associated with an increased risk of cardiovascular morbidity and mortality across multiple disease states. Steroids are an important risk factor in the development of this condition with high blood pressure and improved endurance exercise hypertrophic response are important risk factors.
Interestingly, not all steroids affect the left ventricle to the same degree, but research in this area is limited, leaving us to speculate on what can be more damaging AAS. However, it seems the stronger the androgen, most likely promote LVH. Research shows that when inhibitors of 5-AR is given to people with this condition, left ventricular size is reduced, suggesting a key role of DHT in the development of LVH in relation to testosterone. However, some bodybuilders use inhibitors of 5-AR in combination with testosterone, thus negating any applicable benefit this research could provide. There is some good news, however. HVI appears to at least partially resolve itself after discontinuation of the substance (s) offender. Obviously, this does not give license to abuse, but it's encouraging for those who are already experiencing problems in this area.
Let us just some more cardiovascular conditions steroid-induced dyslipidemia, increased red blood cell production, and increased platelet aggregation. Dyslipidemia (poor lipid values) is one of, if not the greatest predictor of atherosclerosis, while atherosclerosis is the # 1 cause of heart attack in the United States. For those of you who are unaware, atherosclerosis is a narrowing of blood vessels by plaque buildup. If the arteries that supply blood to the heart are blocked as a result of this accumulation, the individual will suffer a heart attack. If this occurs in the brain, it is called a stroke. If carried out in the lungs, it is pulmonary embolism. Each of these cardiovascular events can cause death or serious long-term deterioration. AAS methylated (usually administered orally) are extremely damaging to the lipid profile, making them a potentially powerful accelerator of atherosclerosis. While not methylated injectables are generally softer in this sense, they are in no way harmless.
Steroids also increase the risk of blood clots in two ways: through an increase in the production of red blood cells (polycythemia) and platelet aggregation improved. In short, the red blood cells (RBC) the body produces, the thicker blood can get. If the viscosity increases too blood, blood flow is restricted, leading to a lower flow rate and an increased risk of clots. In order to avoid intravascular coagulation (clotting), the blood must remain in constant motion. If you are too slow or stopped, it will begin to form clots. AAS also increase the risk of clots directly; by increasing platelet aggregation (clumping together of platelets in the blood). Depending on where a clot / cottages, which can cause heart attack, stroke, pulmonary embolism, etc. is formed
If this is not not sound bad enough, consider the fact that this is only a partial list of health problems attributable to use of steroids. Add growth hormone and insulin in the mix and it only gets worse from there. The problem with many cardiovascular conditions is that they are generally slow to develop, taking years or even decades to reach full maturity and produce cardiovascular events that threaten life / life ends. Besides that, many fail to participate in normal laboratory work (which is necessary for the diagnosis of these problems in the first place), allowing them to sneak by unnoticed and continue to strike without restrictions.
With these possible serious side effects, one could be forgiven for thinking that all bodybuilders are aware of them, however, experience has shown otherwise. When it comes down to it, some bodybuilders just do not want to know the truth, it would force them out of their comfort zone and take personal responsibility for their actions. Therefore, they choose to remain in ignorance / denial and when challenged regarding its use, which often try to confuse the issues while playing the blame game.
Basically, the blame game is played as follows. Instead of admitting that the known health risks of AAS, some people argue that because there are many other potential risk factors (diet, body weight, genetic propensities, use of recreational drugs, etc.) involved in the development of these conditions, it is impossible to determine with certainty the extent that it plays a role in its development AAS. This leaves the door open to point the finger at no risk factors PED as a major cause of cardiovascular health problems in bodybuilders. Although it would be foolish to dismiss the relevance of any risk factors, the presence of a risk factor does not eliminate other.
As mentioned above, serious complications can often take years to manifest, so we are now seeing so many bodybuilders experience heart attacks and strokes in their 40s, often much time after have been removed sport. Given the fact that the most dedicated bodybuilders live a lifestyle of regular weight training, cardiovascular exercise and clean eating, this trend should send an immediate red flag, especially when considering the fact that not athletes use drugs experiencing a similar lifestyle aren 't succumb to the same fate. In fact, they are most often on the opposite end of the spectrum in terms of cardiovascular mortality.
Last year, at my gym alone, there were three bodybuilders-all in their 40 early-mid and a history of which use long-term steroids experienced attacks to the heart. To my knowledge, none of them uses rec. drugs and all had been eating clean for more than 20 years. Stories like this are becoming more and more frequent, with many of my friends / acquaintances who reveal similar events worldwide. Although bodybuilding lifestyle always come with risks, we must not blindly accept as part of the deal. We decide what we are willing to endure, and there is much we can do to minimize the negative effects of this lifestyle on our health.
It's been 8 years since the challenge of "show me the bodies" was made. In the words of Dante Trudel, it seems "the bodies are beginning to accumulate" and it is impossible to deny. Be smart. To learn to differentiate the risks and preventive measures available to you, and instead wonder how he ended up with a stick in its constraints hand and physical normally reserved for someone 25 years older, he will continue to do what he likes, without obstacles and unnecessary concern.
Source: http://www.ironmagazine.com/2016/show-me-the-bodies-performance-enhancing-drugs-and-cardiovascular-risk/
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